WebOpherk et al. (2009) showed that both wildtype and CADASIL-mutated (R133C; 600276.0008) NOTCH3 receptor spontaneously formed oligomers and higher order multimers in vitro and that multimerization was mediated by disulfide bonds. CADASIL-associated mutations significantly enhanced multimerization compared with wildtype. WebSCGB3A1 NOTCH3; Gene Name: secretoglobin, family 3A, member 1: notch 3: Image: No pdb structure: No pdb structure: Gene ... CBFA2T2 CHUK CNTD1 CPNE6 CRIP2 CSNK2B DLL1 EGFL7 FBLN1 GGT6 JAG1 JAG2 KAT2B MAML1 MAML2 MAML3 MPPED2 MYC …
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WebEstablishing a molecular diagnosis in individuals with features of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) and NOTCH3-related disorders Identifying disease-causing variants within the NOTCH3 gene … WebThe NOTCH3 gene provides instructions for making a protein with one end (the intracellular end) that remains inside the cell, a middle (transmembrane) section that spans the cell membrane, and another end (the extracellular end) that projects from the outer surface of … cheap car hire hobart tas
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Webnotch3_jag2 notch1_wnt4 fzd6_wnt4 notch1_jag1 cd46_jag1 notch1_nov notch1_dlk1 fzd9_wnt7a fzd9_wnt1 fzd9_wnt2 gpr25_retn ccl24_ccr2 ccl16_ccr2 ccl2_ccr2 ccl24_ccr3 ccl3_ccr3 ccl5_ccr3 ccl3l1_ccr3 ccl3l3_ccr3 ccl11_ccr3 ccl16_ccr1 ccl3_ccr1 ccl5_ccr1 … WebSCGB3A1; Secretoglobin Family 3A Member 1; UGRP2; Uteroglobin-Related Protein 2; Description From GeneCards: SCGB3A1 (Secretoglobin Family 3A Member 1) is a Protein Coding gene. Diseases associated with SCGB3A1 include Adenoid Hypertrophy and … WebMay 8, 2024 · In addition to Scgb1a1, secretoglobin family members, including Scgb3a1 and Scgb3a2, are expressed in heterogeneous populations of secretory cells and are important to the function of these cells in immune homeostasis and mediation of oxidant-induced … cheap car hire in aberdeen