Phospho perk antibody
WebPhospho-PERK (Thr980) Antibody detects endogenous levels of PERK phosphorylated at threonine 980. Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr980 … Monoclonal Antibody for studying PERK (Thr980) phosphate mouse. Cited in 458 …
Phospho perk antibody
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WebArticle Snippet: An antibody specific for the extracellular domain of Met (anti-hHGFR) was purchased from R&D Systems, Inc. Antibodies against Ki67 were purchased from Abcam, cleaved caspase-3, ERK1/2, and phospho ERK1/2 T202/Y204 (pERK) antibodies, AKT and phospho AKT (S473) were from Cell Signaling. WebOverview Product name Anti-PERK antibody See all PERK primary antibodies Description Rabbit polyclonal to PERK Host species Rabbit Tested applications Suitable for: ICC/IF, WB more details Species reactivity Reacts with: Human Immunogen A synthesized peptide derived from an internal region of human PERK General notes
WebNov 26, 2010 · α-Synuclein has been shown to block ER to Golgi vesicular trafficking in different model systems, 8 and overexpression of α-synuclein can induce ER stress. 8, 9 Finally, ER stress has been documented in dopaminergic neurons of the parkinsonian brain, exemplified by increased levels of phospho-PERK, phospho-eIF2α and caspase-4. 10, 11 … WebProtein kinase-like endoplasmic reticulum kinase (PERK) is an eIF2α kinase and transmembrane protein resident in the endoplasmic reticulum (ER) membrane that couples ER stress signals to translation inhibition (1-3). ER stress increases the activity of PERK, which then phosphorylates eIF2α to promote reduced translation.
WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt. Alias: Fold/Unfold WebThis antibody is predicted to react with mouse and rat based on sequence homology. Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), …
WebPurification Affinity purification using immunogen. Specificity p-PERK (Phospho-Thr 982) Antibody detects endogenous levels of total p-PERK at Thr 982. Immunogen Description …
WebWestern blot - Phospho-PERK-T982 Rabbit pAb (AP0886) Western blot analysis of extracts of 293T cells, using Phospho-PERK-T982 Rabbit pAb (AP0886) at 1:1000 dilution.293T … cibt visumcentrale gmbh berlinWebErk Signaling The MAPK/Erk signaling cascade is activated by a wide variety of receptors involved in growth and differentiation including receptor tyrosine kinases (RTKs), integrins, and ion channels. GPCRs (G-Protein Coupled Receptors) activate the MAPK cascade using a different set of adaptors. dgme human resources phone numberWebMar 21, 2024 · PKR-like ER kinase (PERK, EIF2AK3) is an elF2alpha kinase that inhibits protein translation. PERK is a type one endoplasmic reticulum (ER) membrane protein which is involved in both the integrated stress response (ISR) and unfolded protein response (UPR). Gene Wiki entry for EIF2AK3 Gene Additional gene information for EIF2AK3 Gene HGNC … dgme health insuranceWebSep 17, 2003 · Phospho-specific antibodies were labeled with Alexa Fluor dyes to provide multicolor analysis of different signaling events simultaneously within individual cells. Results Fixing cells with 1.5% formaldehyde followed by permeabilization in methanol gave optimal results for pERK, pp38, pJNK, pStat1, pStat5, and pStat6 staining. dgme hiring packetWebApr 1, 2024 · Western blotting analysis was performed using S351 phospho-specific antibodies, as well as MYC, GST, and p62 antibodies. (L) Densitometric analysis of the immunoblot. ... and treated with PA for the indicated durations. Immunoblot analysis using antibodies against p-PERK, PERK, GFP, LC3B, KEAP1, and ACTB (loading control). dgme forgot employee idWebInvitrogen Anti-Phospho-PERK (Thr982) Polyclonal, Catalog # PA5-40294. Tested in Western Blot (WB), Immunohistochemistry (IHC) and ELISA (ELISA) applications. This … cibt ticsWebThe NeuroMab™ anti-Phospho-PERK (Thr980) antibody detects endogenous levels of PERK phosphorylated at Thr980. Expression Host Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr980 of mouse PERK. Species Reactivity Rat Clonality Monoclonal Host Species Rabbit Isotype c# ibufferedcipher