Phenylsulfonylfuroxan
WebDuan W, Li J, Inks ES, et al. Design, synthesis and antitumor evaluation of novel histone deacetylase (HDAC) inhibitors equipped with phenylsulfonylfuroxan module as nitric oxide (NO) donor. J Med Chem . 2015;89:4325–4338. Web11. dec 2024 · Synthesis of phenylsulfonylfuroxan from benzenethiol was reported previously in ref. [23]. General procedure for the preparation of 4 a–b, 7 a–b, 10 a–b and …
Phenylsulfonylfuroxan
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Web23. apr 2015 · Abstract. On the basis of the strategy of creating multifunctional drugs, a novel series of phenylsulfonylfuroxan-based hydroxamates with histone deacetylase … Web28. okt 2014 · Request PDF Hybrids of Phenylsulfonylfuroxan and Coumarin as Potent Antitumor Agents Sixteen furoxan-based nitric oxide (NO) releasing coumarin derivatives …
WebDuan W et al. Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor. J Med Chem 58:4325-38 (2015). PubMed: 25906087; Customer reviews and Q&As. Show All … Web1. jún 2024 · The compounds were designed through a symbiotic approach using selected phenols and phenylsulfonylfuroxan NO-donor. The antioxidant activities of the hybrid …
Web封面人物在2016年被《江苏教育（教育管理版）》收录，原文总共2页。 Web10. nov 2014 · The NO-releasing capacity and the inhibition of ERK/MAPK pathway signaling may explain the potent antineoplastic activity of these compounds. Sixteen furoxan-based nitric oxide (NO) releasing coumarin derivatives (6a-c, 8a-g, 10a, 13a,b, 15, and 17a,b) were designed, synthesized, and evaluated against the A549, HeLa, A2780, A2780/CDDP, and …
Web重组人HDAC1蛋白 (ab101661) Datasheet. SDS. Submit a review Submit a question References (4) RMB5,246.00. 以上报价是含税价格. 产品规格. 5 µg RMB5,246.00 10 µg RMB6,114.00. 这产品现在没有货存， 有关产品的供货请和我们详情， 请和我们联络。.
WebOn the basis of the strategy of creating multifunctional drugs, a novel series of phenylsulfonylfuroxan-based hydroxamates with histone deacetylase (HDAC) inhibitory and nitric oxide (NO) donating activities were designed, synthesized, and evaluated. The most potent NO donor-HDAC inhibitor (HDACI) hybrid, 5c, exhibited a much greater in vitro ... sevis home country addressWeb5. máj 2024 · Abstract. In this work, five new hybrids ofphenylsulfonylfuroxan merging 3-benzyl coumarin and their seco-B-ringderivatives 2–6were designed andsynthesized. … the tree farm denver coWeb26. nov 2014 · Most derivatives displayed potent antiproliferation activities. Among them, 8b exhibited the strongest antiproliferation activity on the four sensitive cell lines mentioned … the tree farm colorado longmontWeb20. okt 2024 · Specifically, phenylsulfonylfuroxan (FZ) was chosen as the NO donor to synthesize the prodrug dimer precursor (FZ-SS-FZ) by disulfide linkages and ester bonds. … sevis homeland securityWebCompound 8b, a novel coumarin derivative with phenylsulfonylfuroxan group, shows significant antiproliferation activity against lung adenocarcinoma cell with low toxicity. Purpose: This study aims ... the tree farm in longmont coloradoWebA photoredox-catalyzed cascade annulation of methyl(2-(phenylethynyl)phenyl)sulfanes and methyl(2-(phenylethynyl)phenyl)selanes with sulfonyl chlorides was developed. A variety of benzothiophenes and benzoselenophenes were obtained in moderate to good yields at ambient temperature. Organic Chemistry Frontiers HOT articles for 2024 … the tree familyWeb14. júl 2024 · Abstract. Twenty-three new coumarin-furoxan hybrids were synthesized, which exhibited nanomole antiproliferation activities in A2780, A2780/CDDP, MCF-7/ADR, … the tree farm golf shopify