WebWZ35 causes G2/M cell cycle arrest in H1975 cells. We next determined the effect of WZ35 on the growth of H1975 cells. We treated the cells with various concentrations of WZ35 for 24 h and then assessed cell cycle phase distribution. Our results show that WZ35 induced G2/M cell cycle arrest in H1975 (Figure 2A–C). G2/M is an important DNA ... WebRecombinant Rhesus Macaque Growth Arrest And DNA-damage-inducible, Alpha from Creative BioMart. Be the first to write a review! Citations: Description GADD45Ais a member of the GADD45 family of proteins. It is ubiquitously expressed,and induced by DNA damage. Upon induction, GADD45A binds to PCNA, stimulatesDNA excision repair, and …
Gadd45a (growth arrest and DNA-damage-inducible, alpha)
WebApr 13, 2024 · The RNA polymerase II degradation factor Degradation Factor 1 (Def1) is important for DNA damage repair and plays various roles in eukaryotes; however, the biological role in plant pathogenic fungi is still unknown. In this study, we investigated the role of Def1 during the development and infection of the rice blast fungus Magnaporthe … WebER stress has been implicated in a variety of common diseases such as diabetes, ischemia and neurodegenerative disorders. One of the components of the ER stress-mediated apoptosis pathway is C/EBP homologous protein (CHOP), also known as growth arrest- and DNA damage-inducible gene 153 (GADD153). scott group llc
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WebThe growth arrest and DNA damage-inducible protein, GADD34, was identified by its interaction with human inhibitor 1 (I-1), a protein kinase A (PKA)-activated inhibitor of type 1 protein serine/threonine phosphatase (PP1), in a yeast two-hybrid screen of a human brain cDNA library. Recombinant GADD34 (amino acids 233 to 674) bound both PKA ... WebJan 5, 2024 · Orthologous to human GADD45A (growth arrest and DNA damage inducible alpha). [provided by Alliance of Genome Resources, Apr 2024] Expression Broad expression in ovary adult (RPKM 73.1), liver E14 (RPKM 52.4) and 24 other tissues See more Orthologs human all NEW Try the new Gene table WebThe role of their unique C-terminal sequences remains largely unknown. The finding that I-1 forms a stable association, at least in vitro, with the growth arrest and DNA damage … scott group ltd exeter