WebMay 14, 1996 · The unliganded GFP-GR resides in the cytoplasm and translocates to the nucleus in a hormone-dependent manner with ligand specificity similar to that of the native GR receptor. Due to the resistance of the mutant GFP to photobleaching, the translocation process can be studied by time-lapse video microscopy. WebIn post-translational translocation, a secretory protein is completely synthesized by the ribosome in the cytoplasm before the translocation process begins. Independent confirmation that the nascent chain occupies an aqueous pore through the membrane during translocation was obtained using iodide ions as hydrophilic collisional quenchers of ...
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WebCon-clusion The over-expressed miRNA-7 in esophageal cancer cells TE-1 can reduce cisplatin sensitivity by the increased EGFR in nuclear translocation.%目的 探讨微小RNA-7(miRNA-7)过表达对食管癌细胞TE-1顺铂敏感性的影响及其可能机制.方法 用Lipofectmin 2000法向食管癌细胞株TE-1转染组瞬时转染miRNA-7 ... WebHere we assessed the influence of different leader peptides on the display of a premature cytoplasmic folding protein, ankyrin repeat protein (ARP), via the minor coat protein pIII. These peptides include the Sec, SRP and Tat pathways. The results demonstrated that the Sec and SRP pathways were capable of displaying the protein on the viral ... iphone 12 price in guyana
YAP nuclear-cytoplasmic translocation is regulated by
WebApr 3, 2024 · Most transcription factors are located in the cytoplasm. After receiving a signal from the cell membrane signal transduction, transcription factors are activated and then translocated from the cytoplasm into the nucleus where they interact with the corresponding DNA frame (cis-acting elements). ... Nuclear translocation signals that … WebMay 14, 2024 · YAP/TAZ is a master regulator of mechanotransduction whose functions rely on translocation from the cytoplasm to the nucleus in response to diverse physical cues. Substrate stiffness, substrate dimensionality, and cell shape are all input signals for YAP/TAZ, and through this pathway, regulate critical cellular functions and tissue … WebApr 4, 2024 · Hypoxia stress rapidly stimulates Arabidopsis CPK12 and promotes its relocation from the cytoplasm to the nucleus, where it interacts with and phosphorylates … iphone 12 price in ikman