Calkin and tontonoz 2012
Web18 Peter Tontonoz, MD PhD 19 HHMI-UCLA 20 675 Charles Young Dr. MRL 6-770 21 Los Angeles, CA 90095 22 [email protected] 23 . ... (Calkin and Tontonoz, 2012; Hong and Tontonoz, 2014). In 43 addition to their ability to activate the expression of genes linked to lipid metabolism, LXRs also have WebCalkin, A. C., & Tontonoz, P. (2012). Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. Nature Reviews Molecular Cell Biology, …
Calkin and tontonoz 2012
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WebJul 27, 2024 · The TOF is calculated as an average value, dividing all molecules converted in a given period by the number of sites. This approach conditions the resulting TOF as it … Webcellular cholesterol (Calkin and Tontonoz, 2012). LXR receptors are important transcriptional regulators in macrophages that activate or repress gene expression upon engulfment of apoptotic cells, including apoptotic neutrophils (Hong et al., 2012). Under steady-state conditions, efficient clearance of
WebFamilial cutaneous and subcutaneous tumoral calcifications are a recognized entity of unknown pathogenesis. The course of calcinosis and various treatments are discussed …
WebPeter Tontonoz is the Frances and Albert Piansky Endowed Chair and Distinguished Professor of Pathology and Laboratory Medicine and of Biological Chemistry. Dr. … WebThe impact of the LXR pathway on both cholesterol metabolism and atherosclerosis is discussed, with a focus on cholesterol regulation and inflammation. First discovered as orphan receptors, liver X receptors (LXRs) were subsequently identified as the nuclear receptor target of the cholesterol metabolites, oxysterols. There are 2 LXR receptors …
WebMar 9, 2024 · The nuclear receptor liver X receptors (LXRs) upregulated a series of genes, including Abcg5, Abcg8, Abca1, and so on, which promote coordinated mobilization of excess cholesterol from cells and from the body [Reviewed in Calkin and Tontonoz (2012)], making it a potentially therapeutic target for the treatment of metabolic and …
WebCalkin Anna C, Tontonoz Peter Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR. Nature Reviews. Molecular Cell Biology. 2012; … eighth\u0027s h8WebAug 1, 2010 · The impact of the LXR pathway on both cholesterol metabolism and atherosclerosis is discussed, with a focus on cholesterol regulation and inflammation. First discovered as orphan receptors, liver X receptors (LXRs) were subsequently identified as the nuclear receptor target of the cholesterol metabolites, oxysterols. There are 2 LXR … eighth\u0027s h9WebJan 6, 2016 · Gut 2012; 61:1701–7. 10.1136/gutjnl-2011-301689 [PMC free article] [Google Scholar] 28. Folch J, Lees M, Sloane Stanley GH. A simple method ... Calkin AC, Tontonoz P. Transcriptional integration of metabolism by … fomc this weekWebOct 16, 2024 · Clays are known to have promising adsorbing characteristics, and are used as feed additives to overcome the negative effects of mycotoxicosis in livestock farming. … fomc tickerWebMar 14, 2012 · Nuclear receptors are integrators of hormonal and nutritional signals, mediating changes to metabolic pathways within the body. Given that modulation of lipid … eighth\\u0027s h8WebMar 11, 2024 · Calkin AC, Tontonoz P (2012) Transcriptional integration of metabolism by the nuclear sterol‐activated receptors LXR and FXR. Nat Rev Mol Cell Biol 13: 213–224 [Europe PMC free article] [Google Scholar] Cohen JC, Horton JD, Hobbs HH (2011) Human fatty liver disease: old questions and new insights. eighth\u0027s haWebJun 29, 2024 · Calkin & Tontonoz, 2012), was similar between two genotypes under re-feeding condition (Fig 1C). The nuclear form of SREBP-1 (SREBP-1N) protein was … eighth\\u0027s h9