WebJun 1, 2024 · The reaction of 2-(3-oxoisobenzofuran-1(3H)-ylidene)malononitrile, generated from phthalic anhydride and malononitrile, with different binucleophiles led to the formation of spiro heterocycles possessing a phthalide ring system in good yields. WebReactions of α-chlorobenzyl isocyanates and 1-aryl-2,2,2-trifluoro-1-chloroethyl isocyanates with N,N-disubstituted cyanothioacetamides gave 3,4-dihydro-2H-1,3-thiazin-4-ones and 3-aryl-2-cyano-4,4,4-trifluorobut-2-enethioamides. The effect of substituents in the reactant molecules on the reaction course and product ratio was studied.
Recyclization of Maleimides by Binucleophiles as a General
WebNov 3, 2024 · Moreover, β-chloroenaldehyde 1 reacted with some 1,4-binucleophiles namely o-phenylenediamine, 1,6-diaminopyridone, o-aminophenol and o-aminothiophenol leading to benzodiazepine, pyrido[1,2-b][1,2,4]triazepine, benzoxazepine and benzothiazepine bearing the pyrimidine moiety through NH linkage. The antimicrobial … WebThe multicomponent reaction (MCR) of arylglyoxal, 4-hydroxycoumarin, and various cyclic 1,3-C,N-binucleophiles in acetic acid under microwave conditions provides fused five- … chinese shrimp balls recipe
2012 OPEN ACCESS molecules
WebA tertiary amine-catalyzed formal (3+n) annulation of 2-(acetoxymethyl)buta-2,3-dienoate with 1,n-binucleophiles has been developed, which provides a facile entry to heterocyclic compounds. The mechanism, involving tandem SN2′–SN2′ substitution and Michael addition, has also been established. Webbinucleophiles, the initial C −N10-23, C −O6,8,24, and C −S8,25 bonds formation occurs, and there are few studies on the formation of a C–C bond, an important structural unit of organic chemistry. 3.1. Reactions with , -binucleophiles WebThe 1,3-bielectrophilic character of the MBH acetate and bromide was further explored with various 1,3-binucleophiles to construct various oxa-, thia- and aza-heterocycles. These … chinese shrimp dishes